RealWorld Dynamix™: Progressive Forms of MS US 2018 Spotlight II

Real time dynamix

In the recent RealWorld Dynamix™: Progressive Forms of Multiple Sclerosis (US) patient chart audit (n=755 patients), Genentech’s Ocrevus was a common alternative or “back up” disease-modifying therapy (DMT) for secondary progressive multiple sclerosis (SPMS) patients that went on to be treated with a different DMT. Competition within the SPMS patient segment may soon increase substantially with a March 2019 PDUFA date anticipated for Novartis’ Mayzent (siponimod), currently under review for a first-in-market SPMS label. Based upon Spherix’s audit data, Mayzent, if approved, would appear to represent a greater competitive switch threat to Ocrevus within the active compared to the not active SPMS segment. See complimentary highlights from the full report below.

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