Though Cosentyx significantly leads the PsO market in biologic patient share and satisfaction; over 100 surveyed US dermatologists’ projected share at six months out reveals the two IL-17 inhibitors as neck and neck.

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CAMBRIDGE, Mass., Nov. 29, 2016 /PRNewswire/ — At just over six months post launch, US dermatologists report a significant increase in familiarity with Eli Lilly’s IL-17 inhibitor, coupled with a significant increase in the Taltz user base from prior quarters. Current users of Taltz expect to double their use in the next three months while one-third of all non-users intend to trial Taltz within the same time frame.

With increased trial and familiarity, the battle for IL-17 domination in PsO ensues as dermatologists continue their struggle to distinguish the two IL-17 inhibitors in the PsO market. Though Cosentyx benefits from its first-to-market status and dermatologist comfort, Taltz appears to be making headway as a more efficacious option with slightly more convenient dosing options, and a high quality patient support program.

Furthermore, projected biologic patient share in the next six months reveals that US dermatologists anticipate Taltz will catch up to Cosentyx. Indeed, the two IL-17 inhibitors are anticipated to each capture a similar amount of biologic treated PsO patients by the first half of the new year. Promising for both drugs is that the entire class of IL-17s is expected to increase, primarily off-setting anti-TNF agents but also stopping Stelara in its tracks.

Potential new market entrants, including Valeant’s Siliq (brodalumab), Janssen’s guselkumab, Boehringer Ingelheim/AbbVie’s risankizumab, Merck/Sun Pharma’s tildrakizumab, and UCB’s bimekizumab will undoubtedly impact the ever-evolving PsO landscape. Indeed, though the fate of Siliq is yet to be revealed, two-thirds of dermatologists agree that the associated suicide risk is a huge deterrent to their use. Despite this, half agree that if the product is priced cheaper than Taltz and Cosentyx, they will prescribe it prior to those agents.

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